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1 .GTX104634 COX1 antibody [C3], C-term

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COX1 antibody [C3], C-term


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC-P, WB
  • Species reactivityHuman
Cat No: GTX104634
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Anti-COX1 antibody [C3], C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX104634
  • Anti-COX1 antibody [C3], C-term used in Western Blot (WB). GTX104634
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  • Application Information: COX1 antibody [C3], C-term

Catalog Number GTX104634
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Product Name COX1 antibody [C3], C-term
See all COX1 products
ApplicationsIHC-P, WB
Application Note
Suggested dilutionReference
IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*  
Western Blot (WB)1:500-1:3000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size69 kDa (note) IsoForm (7)
Positive Controls293T , A431 , HepG2 , Molt-4 , Raji
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: COX1 antibody [C3], C-term

Full Nameprostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
BackgroundProstaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq]
SynonymsCOX1 antibody, COX3 antibody, PCOX1 antibody, PGG/HS antibody, PGHS-1 antibody, PGHS1 antibody, PHS1 antibody, PTGHS antibody, PTGS1 antibody, prostaglandin G/H synthase 1 antibody, cyclooxygenase-1 antibody, PGH synthase 1 antibody, COX-1 antibody, prostaglandin H2 synthase 1 antibody, PHS 1 antibody, prostaglandin G/H synthase and cyclooxygenase antibody, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
Cellular LocalizationMicrosome membrane; Peripheral membrane protein , Endoplasmic reticulum membrane; Peripheral membrane protein
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COX1. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: COX1 antibody [C3], C-term

Storage Buffer1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Breast > Other
  • Cancer > Type of cancer > Gastrointestinal > Stomach
  • Cancer > Type of cancer > Lung > Other
  • Cancer > Type of cancer > Ovarian
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COX1 antibody [C3], C-term validated data
  • Anti-COX1 antibody [C3], C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX104634
    • GTX104634 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using PTGS1 (GTX104634) antibody at 1:100 dilution.
      Top
  • Anti-COX1 antibody [C3], C-term used in Western Blot (WB). GTX104634
    • GTX104634 WB Image
      Sample(30 μg of whole cell lysate)
      A:MOLT4(GTX27912)
      10% SDS PAGE
      GTX104634 diluted at 1:500
      Top
  • Anti-COX1 antibody [C3], C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX104634
    • GTX104634 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using PTGS1 (GTX104634) antibody at 1:100 dilution.
      Top
  • Anti-COX1 antibody [C3], C-term used in Western Blot (WB). GTX104634
    • GTX104634 WB Image
      Sample(30 μg of whole cell lysate)
      A:MOLT4(GTX27912)
      10% SDS PAGE
      GTX104634 diluted at 1:500
      Top
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Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensPTGS15742P23219176805NP_00125809363.3
Homo sapiensPTGS15742P23219176805NP_00125809456.09
Homo sapiensPTGS15742P23219176805NP_00125809551.92
Homo sapiensPTGS15742P23219176805NP_00125829651.92
Homo sapiensPTGS15742P23219176805NP_00125829761.94
Homo sapiensPTGS15742P23219176805NM_000962NP_00095368.7
Homo sapiensPTGS15742P23219176805NM_080591NP_54215864.52
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-PBS.pdf
    MSDS-Thimerosal.pdf
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All products are for research use only—Not for use in diagnostic procedures.