|Full Name||COX15 homolog, cytochrome c oxidase assembly protein (yeast)|
|Product Description||Rabbit Polyclonal antibody to COX15 (COX15 homolog, cytochrome c oxidase assembly protein (yeast))|
|Background||Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq]|
|Synonyms||COX15 antibody, cytochrome c oxidase subunit 15 antibody, cytochrome c oxidase assembly protein COX15 homolog antibody, "COX15 homolog, cytochrome c oxidase assembly protein (yeast) antibody"|
|Cellular Localization||Mitochondrion membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human COX15. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (91%), Bovine (93%)|