COX5A antibody [N1C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||17 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cytochrome c oxidase subunit Va|
|Product Description||Rabbit Polyclonal antibody to COX5A (cytochrome c oxidase subunit Va)|
|Background||Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq]|
|Synonyms||COX antibody, COX-VA antibody, VA antibody, COX5A antibody, "cytochrome c oxidase subunit 5A, mitochondrial antibody", mitochondrial cytochrome c oxidase subunit Va antibody, cytochrome c oxidase polypeptide Va antibody, "cytochrome c oxidase polypeptide, mitochondrial antibody", cytochrome c oxidase subunit Va antibody|
|Cellular Localization||Mitochondrion inner membrane|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human COX5A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Dog, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (93%), Xenopus laevis (86%), Dog (94%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (93%)|