| Full Name | crumbs homolog 1 (Drosophila) |
| Product Description | Rabbit Polyclonal antibody to CRB1 |
| Background | This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012] |
| Synonyms | crumbs homolog 1 (Drosophila) Antibody , LCA8 Antibody , RP12 Antibody |
| Specificity | Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | CRB1 |
| Isotype | IgG |
| Immunogen | The immunogen corresponding to a region within amino acids 651 and 700 of human CRB1. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |