|Product Description||Rabbit Polyclonal antibody to CRBN (cereblon)|
|Background||This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CRBN antibody , CRBN antibody , MRT2 antibody , MRT2A antibody , cereblon antibody|
|Cellular Localization||Cytoplasm , Membrane; Peripheral membrane protein , Cytoplasm , Membrane|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human CRBN. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (97%), Rhesus Monkey (99%), Bovine (90%)|