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Catalog Number
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GTX130379
(
0
)
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Product Name
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CREB (phospho Ser133) antibody
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| Applications | WB |
| Application Note |
| Suggested dilution | Reference |
| Western Blot (WB) | 1:500-1:3000* |
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Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Target Size | 37 kDa (note)
 (3)
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| Positive Controls | PC-12 , A431 (200 ng/ml EGF treatment for 30 min) , NIH-3T3 (5 ng/ml PDGF treatment for 15 min) , NIH-3T3 , NIH-3T3 (0.1 μg/ml hFGF2 treatment for 10 min) |
| Form Supplied | Liquid |
| Concentration | 0.39
mg/ml
(Please refer to the vial label for the specific concentration) |
| Purification | Purified by antigen-affinity chromatography. |
| Full Name | cAMP responsive element binding protein 1 |
| Background | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq] |
| Synonyms | CREB antibody antibody , CREB-1 antibody antibody , CREB1 antibody antibody , cAMP responsive element binding protein 1 antibody antibody |
| Cellular Localization | Nucleus |
| Specificity | This antibody is raised against human CREB phosphorylated at Ser133, and it also may detect the phosphorylated ATF1 protein due to sequence homology. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human CREB (phospho Ser133). The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine |
| Predict Reactivity Note | Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%) |
| Conjugation | Unconjugated |