CREB (phospho Ser133) antibody
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||NIH-3T3 , NIH-3T3 (100 ng/ml hFGF2 treatment for 10 min) , A431 (200 ng/ml EGF, 30 min) , NIH-3T3 (5 ng/ml PDGF, 15 min)|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cAMP responsive element binding protein 1|
|Product Description||Rabbit Polyclonal antibody to CREB (phospho Ser133) (cAMP responsive element binding protein 1)|
|Background||This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]|
|Target||CREB (phospho Ser133)|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human CREB (phospho Ser133). The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)|