| Full Name | cAMP responsive element binding protein 1 |
| Background | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq] |
| Cellular Localization | Nucleus |
| Specificity | This antibody is raised against human CREB phosphorylated at Ser133, and it also may detect the phosphorylated ATF1 protein due to sequence homology. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human CREB (phospho Ser133). The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine |
| Predict Reactivity Note | Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%) |
| Conjugation | Unconjugated |