|Full Name||cAMP responsive element modulator|
|Product Description||Rabbit Polyclonal antibody to CREM (cAMP responsive element modulator)|
|Background||This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq]|
|Synonyms||ICER antibody, MGC111110 antibody, MGC17881 antibody, MGC41893 antibody, hCREM-2 antibody, CREM antibody, cAMP-responsive element modulator antibody, inducible cAMP early repressor ICER antibody, CREM 2alpha-b protein antibody, cAMP response element modulator antibody, CREM 2beta-a protein antibody, cAMP responsive element modulator antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CREM. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Chicken, Bovine|
|Predict Reactivity Note||Dog (91%), Chicken (87%), Bovine (99%)|