|Full Name||corticotropin releasing hormone receptor 2|
|Product Description||Rabbit polyclonal antibody to CRF-RII (corticotropin releasing hormone receptor 2)|
|Background||Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.[supplied by OMIM]|
|Synonyms||CRF2 antibody, CRFR2 antibody, CRHR2 antibody, corticotropin-releasing factor receptor 2 antibody, "CRF2 receptor, beta isoform antibody", CRH-R2 antibody, corticotropin releasing hormone receptor 2 antibody|
|Cellular Localization||Cell membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRF-RII. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (100%)|