CSE1L antibody [GT5111]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||293T , A431 , HeLa , HepG2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||CSE1 chromosome segregation 1-like (yeast)|
|Product Description||Mouse Monoclonal antibody [GT5111] to CSE1L (CSE1 chromosome segregation 1-like (yeast))|
|Background||Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]|
|Synonyms||CAS Antibody, XPO2 Antibody, CSE1 chromosome segregation 1-like (yeast) Antibody, CSE1 Antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (95%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)|