|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||51 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||c-src tyrosine kinase|
|Product Description||Rabbit polyclonal antibody to c-Src (c-src tyrosine kinase)|
|Background||Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.|
|Synonyms||MGC117393 antibody, CSK antibody, protein-tyrosine kinase CYL antibody, tyrosine-protein kinase CSK antibody, C-Src kinase antibody, c-src tyrosine kinase antibody|
|Cellular Localization||Cytoplasm , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CSK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (99%), Zebrafish (88%), Pig (99%), Chicken (95%), Rhesus Monkey (100%), Bovine (99%)|