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CTCF antibody [1D11]

Anti-CTCF antibody [1D11] used in Western Blot (WB). GTX80397

Cat. No. GTX80397

Host

Mouse

Clonality

Monoclonal

Clone Name

1D11

Isotype

IgG1

Application

WB, ELISA

Reactivity

Human, Mouse, Monkey
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

83 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human CTCF expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CCCTC-binding factor , MRD21

Cellular Localization

nucleoplasm

Background

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-CTCF antibody [1D11] used in Western Blot (WB). GTX80397

GTX80397 WB Image

WB analysis of A31 (1), MCF-7 (2), HeLa (3), HCT116 (4), Jurkat (5), NIH3T3 (6), and Cos7 (7) cell lysate using GTX80397 CTCF antibody [1D11].

REFERENCE

There are currently no references for CTCF antibody [1D11] (GTX80397). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CTCF antibody [1D11] (GTX80397). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399