|Full Name||CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2|
|Product Description||Rabbit Polyclonal antibody to CTDSP2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2)|
|Background||Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
|Synonyms||OS4 antibody, PSR2 antibody, SCP2 antibody, CTDSP2 antibody, protein OS-4 antibody, conserved gene amplified in osteosarcoma antibody, NLI-interacting factor 2 antibody, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody, nuclear LIM interactor-interacting factor 2 antibody, small CTD phosphatase 2 antibody, small C-terminal domain phosphatase 2 antibody, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CTDSP2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (85%), Pig (99%), Rhesus Monkey (100%), Bovine (99%)|