Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||45 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , mouse liver , rat liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cystathionase (cystathionine gamma-lyase)|
|Product Description||Rabbit Polyclonal antibody to CTH (cystathionase (cystathionine gamma-lyase))|
|Background||This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||MGC9471 antibody, CTH antibody, homoserine deaminase antibody, cysteine desulfhydrase antibody, homoserine dehydratase antibody, cystathionine gamma-lyase antibody, gamma-cystathionase antibody, cystathionase (cystathionine gamma-lyase) antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CTH. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (86%), Bovine (89%)|