|Full Name||chemokine (C-X-C motif) receptor 3|
|Product Description||Rabbit Polyclonal antibody to CXCR3|
|Background||This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]|
|Synonyms||CD182 Antibody, IP10-R Antibody, Mig-R Antibody, CKR-L2 Antibody, chemokine (C-X-C motif) receptor 3 Antibody, CD183 Antibody, CMKAR3 Antibody, GPR9 Antibody, MigR Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from mouse CXCR3|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Rabbit, Guinea pig, Pig, Dog|