|Full Name||cytoplasmic FMR1 interacting protein 1|
|Product Description||Rabbit Polyclonal antibody to CYFIP1 (cytoplasmic FMR1-interacting protein 1)|
|Background||Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. |
|Synonyms||FLJ45151 antibody, P140SRA-1 antibody, SHYC antibody, SRA1 antibody, CYFIP1 antibody, sra-1 antibody, cytoplasmic FMRP interacting protein 1 antibody, selective hybridizing clone antibody, specifically Rac1-associated protein 1 antibody, cytoplasmic FMR1-interacting protein 1 antibody, cytoplasmic FMR1 interacting protein 1 antibody|
|Cellular Localization||Cytoplasm , perinuclear region , Cell projection , lamellipodium , ruffle , Cell junction , synapse , synaptosome |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human CYFIP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (93%), Bovine (100%)|