|Full Name||cytochrome P450, family 1, subfamily B, polypeptide 1|
|Product Description||Rabbit Polyclonal antibody to CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq]|
|Synonyms||CP1B antibody, GLC3A antibody, P4501B1 antibody, CYP1B1 antibody, aryl hydrocarbon hydroxylase antibody, microsomal monooxygenase antibody, cytochrome P450 1B1 antibody, xenobiotic monooxygenase antibody, cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) antibody, flavoprotein-linked monooxygenase antibody, cytochrome P450, family 1, subfamily B, polypeptide 1 antibody|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP1B1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (84%), Dog (82%), Rhesus Monkey (94%), Bovine (82%)|