|Full Name||cytochrome P450, family 26, subfamily A, polypeptide 1|
|Product Description||Rabbit Polyclonal antibody to CYP26A1 (cytochrome P450, family 26, subfamily A, polypeptide 1)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq]|
|Synonyms||CP26 antibody, CYP26 antibody, P450RAI antibody, P450RAI1 antibody, CYP26A1 antibody, cytochrome P450 26A1 antibody, cytochrome P450RAI antibody, "P450, retinoic acid-inactivating, 1 antibody", retinoic acid 4-hydroxylase antibody, "cytochrome P450, subfamily XXVIA, polypeptide 1 antibody", retinoic acid-metabolizing cytochrome antibody, cytochrome P450 retinoic acid-inactivating 1 antibody, hP450RAI antibody, "cytochrome P450, family 26, subfamily A, polypeptide 1 antibody"|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP26A1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (92%), Pig (97%), Chicken (83%), Rhesus Monkey (100%), Bovine (96%)|