|Full Name||cytochrome P450, family 2, subfamily C, polypeptide 8|
|Product Description||Rabbit Polyclonal antibody to CYP2C8 (cytochrome P450, family 2, subfamily C, polypeptide 8)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]|
|Synonyms||CPC8 antibody, CYPIIC8 antibody, MP-12/MP-20 antibody, CYP2C8 antibody, cytochrome P450 IIC2 antibody, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 antibody, flavoprotein-linked monooxygenase antibody, s-mephenytoin 4-hydroxylase antibody, cytochrome P450 MP-20 antibody, P450 form 1 antibody, cytochrome P450 form 1 antibody, cytochrome P450 MP-12 antibody, cytochrome P450 2C8 antibody, microsomal monooxygenase antibody, xenobiotic monooxygenase antibody, cytochrome P450, family 2, subfamily C, polypeptide 8 antibody|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP2C8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (93%)|