|Full Name||cytochrome P450, family 3, subfamily A, polypeptide 43|
|Product Description||Rabbit Polyclonal antibody to CYP3A43 (cytochrome P450, family 3, subfamily A, polypeptide 43)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||MGC119315 antibody, MGC119316 antibody, CYP3A43 antibody, "cytochrome P450, subfamily IIIA, polypeptide 43 antibody", cytochrome P450 3A43 antibody, cytochrome P450 polypeptide 43 antibody, "cytochrome P450, family 3, subfamily A, polypeptide 43 antibody"|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP3A43. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (96%)|