|Full Name||cytochrome P450, family 51, subfamily A, polypeptide 1|
|Product Description||Rabbit Polyclonal antibody to CYP51A1 (cytochrome P450, family 51, subfamily A, polypeptide 1)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CP51 antibody, CYP51 antibody, CYPL1 antibody, LDM antibody, P450-14DM antibody, P450L1 antibody, CYP51A1 antibody, sterol 14-alpha demethylase antibody, lanosterol 14-alpha demethylase antibody, lanosterol 14-alpha-demethylase antibody, cytochrome P45014DM antibody, "cytochrome P450, 51 (lanosterol 14-alpha-demethylase) antibody", cytochrome P450 51A1 antibody, CYPLI antibody, cytochrome P450LI antibody, cytochrome P450-14DM antibody, "cytochrome P450, family 51, subfamily A, polypeptide 1 antibody"|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP51A1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (84%), Chicken (87%), Chimpanzee (98%), Bovine (94%)|