|Full Name||cytochrome P450, family 7, subfamily A, polypeptide 1|
|Product Description||Rabbit polyclonal antibody to CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. [provided by RefSeq]|
|Synonyms||CP7A antibody, CYP7 antibody, CYPVII antibody, MGC126826 antibody, MGC138389 antibody, CYP7A1 antibody, cytochrome P450 7A1 antibody, "cytochrome P450, subfamily VIIA polypeptide 1 antibody", cholesterol 7-alpha-monooxygenase antibody, cholesterol 7-alpha-hydroxylase antibody, "cytochrome P450, family 7, subfamily A, polypeptide 1 antibody"|
|Cellular Localization||Endoplasmic reticulum membrane , Microsome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CYP7A1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (83%), Rat (82%), Pig (85%), Rabbit (83%), Rhesus Monkey (94%), Bovine (88%)|