|Full Name||caldesmon 1|
|Product Description||Rabbit Polyclonal antibody to Caldesmon (caldesmon 1)|
|Background||This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, MGC21352 antibody, NAG22 antibody, CALD1 antibody, caldesmon antibody, caldesmon 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Caldesmon. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (83%), Rabbit (86%), Bovine (89%)|