|Product Description||Rabbit Polyclonal antibody to Calpastatin (calpastatin)|
|Background||The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length natures of only some have been determined. [provided by RefSeq]|
|Synonyms||BS-17 antibody, MGC9402 antibody, CAST antibody, calpastatin antibody, calpain inhibitor antibody, sperm BS-17 component antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Calpastatin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rabbit (80%), Bovine (80%)|