|Full Name||carbonic anhydrase XII|
|Product Description||Rabbit polyclonal antibody to CA12 (carbonic anhydrase XII)|
|Background||Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||CAXII antibody, FLJ20151 antibody, HsT18816 antibody, CA12 antibody, carbonic anhydrase 12 antibody, carbonate dehydratase XII antibody, CA-XII antibody, tumor antigen HOM-RCC-3.1.3 antibody, carbonic dehydratase antibody, carbonic anhydrase XII antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Carbonic anhydrase XII. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rabbit, Rhesus Monkey|
|Predict Reactivity Note||Human (100%), Rabbit (80%), Rhesus Monkey (97%)|