Cardiac Troponin I antibody [N1C3-2]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||24 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse heart , rat heart|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||troponin I type 3 (cardiac)|
|Product Description||Rabbit Polyclonal antibody to Cardiac Troponin I (troponin I type 3 (cardiac))|
|Background||Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]|
|Synonyms||CMD1FF antibody, CMD2A antibody, CMH7 antibody, MGC116817 antibody, RCM1 antibody, TNNC1 antibody, cTnI antibody, TNNI3 antibody, troponin I, cardiac muscle antibody, troponin I type 3 (cardiac) antibody, Troponin I (cardiac) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cardiac Troponin I. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Cat, Pig, Bovine|
|Predict Reactivity Note||Dog (97%), Cat (97%), Pig (95%), Bovine (97%)|