|Full Name||caspase 2, apoptosis-related cysteine peptidase|
|Product Description||Rabbit Polyclonal antibody to Caspase 2 (caspase 2, apoptosis-related cysteine peptidase)|
|Background||This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq]|
|Synonyms||CASP-2 antibody, ICH-1L antibody, ICH-1S antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, CASP2 antibody, protease ICH-1 antibody, neural precursor cell expressed developmentally down-regulated protein 2 antibody, caspase-2 antibody, "protein phosphatase 1, regulatory subunit 57 antibody", "caspase 2, apoptosis-related cysteine peptidase antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Caspase 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Dog (83%), Bovine (81%)|