|Full Name||caspase 4, apoptosis-related cysteine peptidase|
|Product Description||Rabbit Polyclonal antibody to Caspase 4 (caspase 4, apoptosis-related cysteine peptidase)|
|Background||This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, CASP4 antibody, apoptotic cysteine protease Mih1/TX antibody, CASP-4 antibody, caspase 4, apoptosis-related cysteine protease antibody, protease ICH-2 antibody, protease TX antibody, caspase-4 antibody, ICE(rel)-II antibody, caspase 4, apoptosis-related cysteine peptidase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Caspase 4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (96%), Bovine (84%)|