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1 .GTX86945 Caspase 9 (cleaved Asp315) antibody

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Caspase 9 (cleaved Asp315) antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsELISA, IHC, IHC-P, WB
  • Species reactivityHuman
Cat No: GTX86945
Package Price Qty
100 μg USD 319.00
Add to cart
 
  • Anti-Caspase 9 (cleaved Asp315) antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX86945
  • Anti-Caspase 9 (cleaved Asp315) antibody used in Western blot. GTX86945
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  • Datasheet

  • Application Information: Caspase 9 (cleaved Asp315) antibody

Catalog Number GTX86945
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Product Name Caspase 9 (cleaved Asp315) antibody
See all Caspase 9 products
ApplicationsELISA, IHC, IHC-P, WB
Application NoteWe recommend the following starting dilutions:

WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Optimal dilutions should be determined experimentally by the end user.

Predicted Target Size37 kDa (note)
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Specifications: Caspase 9 (cleaved Asp315) antibody

Full Namecaspase 9, apoptosis-related cysteine peptidase
Product DescriptionRabbit polyclonal antibody to Caspase 9 (cleaved Asp315)
BackgroundInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
SynonymsCaspase9, inhibitor of CAD, H13, Caspase 9, DFF-45, DFF1, DNAation factor45 kDa subunit, DNAation factor 45 kDa subunit, DFF45, ICAD, DFF 45, Caspase 9 (cleaved D315), Caspase 9 (cleaved Asp315), Caspase 9 cleaved D315, Caspase 9 cleaved Asp315, Cleaved Caspase 9 (D315), Cleaved Caspase 9 (Asp315)
SpecificityCaspase 9 (Cleaved-Asp315) Antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp315.
HostRabbit
ClonalityPolyclonal
TargetCaspase 9
ImmunogenThe amino acid range of this immunogen is aa285-315 of human Caspase 9 with accession number P55211
Antigen SpeciesHuman
Species ReactivityHuman

  • Storage Conditions: Caspase 9 (cleaved Asp315) antibody

Storage BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at -20 degrees Celcius. Product is stable for at least 1 year.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Diabetes
  • Immunology > Autoimmunity > Autoimmune diseases > Crohn Disease
  • Immunology > Autoimmunity > Autoimmune diseases > Diabetes
  • Signal Transduction > Signaling through enzyme-linked cell surface receptors > PI 3-Kinase
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Caspase 9 (cleaved Asp315) antibody validated data
  • Anti-Caspase 9 (cleaved Asp315) antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX86945
    • GTX86945 IHC-P Image
      Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 9 (Cleaved-Asp315) Antibody. The picture on the right is treated with the synthesized peptide.
      Top
  • Anti-Caspase 9 (cleaved Asp315) antibody used in Western blot. GTX86945
    • GTX86945 WB Image
      Western blot analysis of extracts from 293 cells, treated with Etoposide 25uM 60', using Caspase 9 (Cleaved-Asp315) Antibody. The lane on the right is treated with the synthesized peptide.
      Top
  • Anti-Caspase 9 (cleaved Asp315) antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX86945
    • GTX86945 IHC-P Image
      Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 9 (Cleaved-Asp315) Antibody. The picture on the right is treated with the synthesized peptide.
      Top
  • Anti-Caspase 9 (cleaved Asp315) antibody used in Western blot. GTX86945
    • GTX86945 WB Image
      Western blot analysis of extracts from 293 cells, treated with Etoposide 25uM 60', using Caspase 9 (Cleaved-Asp315) Antibody. The lane on the right is treated with the synthesized peptide.
      Top
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