Caspr2 antibody [N2N3]
|Applications||ICC/IF, IHC-Fr, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||148 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||contactin associated protein-like 2|
|Product Description||Rabbit Polyclonal antibody to Caspr2 (contactin associated protein-like 2)|
|Background||This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness. [provided by RefSeq]|
|Synonyms||AUTS15 antibody, CASPR2 antibody, CDFE antibody, DKFZp781D1846 antibody, NRXN4 antibody, PTHSL1 antibody, CNTNAP2 antibody, contactin-associated protein-like 2 antibody, cell recognition molecule Caspr2 antibody, contactin-associated protein 2 antibody, homolog of Drosophila neurexin IV antibody, contactin associated protein-like 2 antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Caspr2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|