|Product Description||Rabbit Polyclonal antibody to Catalase (catalase)|
|Background||This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]|
|Synonyms||MGC138422 antibody, MGC138424 antibody, CAT antibody, catalase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Catalase. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Dog, Pig, Chicken, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (93%), Rat (92%), Zebrafish (82%), Dog (95%), Pig (94%), Chicken (87%), Bovine (93%), Guinea pig (91%)|