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1 .GTX19555 Cathepsin D antibody

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Cathepsin D antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsELISA, WB
  • Species reactivityHuman
  • Publication  ( 3 )
Cat No: GTX19555
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1 mlUSD 339.00
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  • Application Information: Cathepsin D antibody

Catalog Number GTX19555
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Publication ( 3 )
Product Name Cathepsin D antibody
See all Cathepsin D products
ApplicationsELISA, WB
Application Note
Suggested dilutionReference
ELISA1:16000*  
Western Blot (WB)Assay-dependent dilution Y
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Form SuppliedLiquid
Concentration20.60 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by Ammonium sulfate precipitation

  • Specifications: Cathepsin D antibody

Full Namecathepsin D
BackgroundThis gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008]
SynonymsCTSD Antibody , CPSD Antibody , CLN10 Antibody
Cellular LocalizationLysosomal
SpecificityWhen tested by immunoblot analysis at a dilution of 1:4,000 the antibody reacts with human liver cathepsinD and does not react with cathepsins B, H and L.
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenMature form Cathepsin D
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: Cathepsin D antibody

Storage BufferPBS, 0.05% sodium azide
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Disease Related > Parkinson Disease
  • Neuroscience > Disorder > Alzheimer's disease
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Cathepsin D antibody validated data
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  • Reference for Cathepsin D antibody
Application References Application Reactivity
Wang AL et al. Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration. PLoS One 4 (4):e5304 (2009).
Chen H et al. Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity. Invest Ophthalmol Vis Sci 50 (4):1895-902 (2009). WB
Wang AL et al. Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration. PLoS One 4 (1):e4160 (2009). WB
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