|Full Name||cathepsin D|
|Product Description||Rabbit Polyclonal antibody to Cathepsin D (cathepsin D)|
|Background||This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq]|
|Synonyms||CLN10 antibody, CPSD antibody, MGC2311 antibody, CTSD antibody, cathepsin D antibody, lysosomal aspartyl peptidase antibody, lysosomal aspartyl protease antibody, ceroid-lipofuscinosis, neuronal 10 antibody|
|Cellular Localization||Lysosome , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cathepsin D. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (83%), Dog (90%), Pig (85%), Rhesus Monkey (94%), Bovine (83%)|