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  • Cathepsin D (cleaved Leu169) antibody

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1 .GTX86942 Cathepsin D (cleaved Leu169) antibody

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Cathepsin D (cleaved Leu169) antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsELISA, WB
  • Species reactivityHuman
Cat No: GTX86942
Package Price Qty
100 μg USD 339.00
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  • Anti-Cathepsin D (cleaved Leu169) antibody used in Western Blot (WB). GTX86942
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  • Datasheet

  • Application Information: Cathepsin D (cleaved Leu169) antibody

Catalog Number GTX86942
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Product Name Cathepsin D (cleaved Leu169) antibody
See all Cathepsin D products
ApplicationsELISA, WB
Application NoteWe recommend the following starting dilutions:

WB: 1:500~1:1000
ELISA: 1:40000

Optimal dilutions should be determined experimentally by the end user.

Predicted Target Size27 kDa (note)
Form SuppliedLiquid
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Specifications: Cathepsin D (cleaved Leu169) antibody

Full Namecathepsin D
BackgroundAcid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
SynonymsCATD, MGC2311, CPSD, CLN10, CATD (cleaved L169), CATD (cleaved Leu169), CATD cleaved L169, CATD cleaved Leu169, Cleaved CATD (L169), Cleaved CATD (Leu169)
Cellular LocalizationIdentified by mass spectrometry in melanosome fractions from stage I to stage IV.
SpecificityCATD (heavy chain,Cleaved-Leu169) Antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Leu169.
HostRabbit
ClonalityPolyclonal
ImmunogenThe antiserum was produced against synthesized peptide derived from human CATD.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: Cathepsin D (cleaved Leu169) antibody

Storage BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Disease Related > Parkinson Disease
  • Neuroscience > Disorder > Alzheimer's disease
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Cathepsin D (cleaved Leu169) antibody validated data
  • Anti-Cathepsin D (cleaved Leu169) antibody used in Western Blot (WB). GTX86942
    • GTX86942 WB Image
      Western blot analysis of extracts from 293/A549/JurKat cells, treated with etoposide 25uM 1h, using CATD (heavy chain,Cleaved-Leu169) Antibody. The lane on the right is treated with the synthesized peptide.
      Top
  • Anti-Cathepsin D (cleaved Leu169) antibody used in Western Blot (WB). GTX86942
    • GTX86942 WB Image
      Western blot analysis of extracts from 293/A549/JurKat cells, treated with etoposide 25uM 1h, using CATD (heavy chain,Cleaved-Leu169) Antibody. The lane on the right is treated with the synthesized peptide.
      Top
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