Full Name | cathepsin D |
Background | Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
Synonyms | CATD, MGC2311, CPSD, CLN10, CATD (cleaved L169), CATD (cleaved Leu169), CATD cleaved L169, CATD cleaved Leu169, Cleaved CATD (L169), Cleaved CATD (Leu169) |
Cellular Localization | Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Specificity | CATD (heavy chain,Cleaved-Leu169) Antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Leu169. |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized peptide derived from human CATD. |
Antigen Species | Human |
Species Reactivity | Human |
Conjugation | Unconjugated |