|Full Name||cathepsin K|
|Product Description||Rabbit polyclonal antibody to Cathepsin K (cathepsin K)|
|Background||The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]|
|Synonyms||CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, MGC23107 antibody, PKND antibody, PYCD antibody, CTSK antibody, cathepsin K antibody, cathepsin O antibody, cathepsin X antibody, cathepsin O2 antibody, cathepsin O1 antibody|
|Target||Cathepsin K |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cathepsin K. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Dog, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (88%), Rat (88%), Dog (91%), Pig (94%), Rabbit (90%), Rhesus Monkey (95%), Bovine (91%)|