Choline Acetyltransferase antibody [N1N3]
|Applications||ICC/IF, IHC-Fr, IHC-P, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||83 kDa (note)
|Positive Controls||H1299 , U87-MG , SK-N-SH , IMR32 , SK-N-AS , Mouse brain , Rat liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||choline O-acetyltransferase|
|Product Description||Rabbit polyclonal antibody to CHAT (choline acetyltransferase)|
|Background||This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq]|
|Synonyms||CHOACTASE antibody, CMS1A antibody, CMS1A2 antibody, CHAT antibody, choline O-acetyltransferase antibody, acetyl CoA:choline O-acetyltransferase antibody, choline acetylase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Choline Acetyltransferase. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (94%)|