| Full Name | claudin 3 |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008] |
| Synonyms | C7orf1 Antibody , CPETR2 Antibody , RVP1 Antibody , CPE-R2 Antibody , claudin 3 Antibody , CLDN3 Antibody , HRVP1 Antibody |
| Specificity | The antibody detects endogenous levels of Claudin 3 only when phosphorylated at tyrosine 219. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 219 (R-K-D-Y(p)-V) derived from Human Claudin 3. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |