Cofilin 1 antibody [GT567]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||19 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , A375 , NIH-3T3 , JC , BCL-1|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||cofilin 1 (non-muscle)|
|Product Description||Mouse Monoclonal antibody to Cofilin 1 (cofilin 1 (non-muscle))|
|Background||Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM]|
|Cellular Localization||Nucleus matrix , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cofilin 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (99%), Pig (99%), Sheep (99%), Rhesus Monkey (99%), Bovine (99%)|