|Full Name||collagen, type II, alpha 1|
|Product Description||Rabbit Polyclonal antibody to Collagen II (collagen, type II, alpha 1)|
|Background||This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq]|
|Synonyms||ANFH antibody, AOM antibody, COL11A3 antibody, MGC131516 antibody, SEDC antibody, COL2A1 antibody, cartilage collagen antibody, collagen alpha-1(II) chain antibody, chondrocalcin antibody, "collagen II, alpha-1 polypeptide antibody", alpha-1 type II collagen antibody, "collagen, type II, alpha 1 antibody"|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Collagen II. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (96%), Xenopus laevis (88%), Dog (100%), Rabbit (100%), Chicken (95%), Bovine (100%)|