| Full Name | collagen type IV alpha 1 |
| Product Description | Mouse Monoclonal antibody [COL-94] to Collagen IV |
| Background | Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas. |
| Synonyms | 120070, FLJ22259, MGC42377, 1285, P02462, 1284, ATS, 1286, COL4A5, 120130, P08572, COL4A4, 1287, CA54, Collagen IV, COL4A2, CA44, 120131, Q01955, COL4A3, 301050, 120090, 1282, ASLN, COL4A1, P29400, P53420, arresten |
| Cellular Localization | Cell surface (Potential). |
| Specificity | Using immunohistochemical staining of basal laminae, the antibody recognizes an epitope located on the α1 and/or α2 chains of human collagen type IV. The antibody shows reactivity with native primate collagen type IV in ELISA and dot blot assay. Using the dot blot technique, the antibody shows no cross-reactivity with human collagen types I, II, III, V, VI and VII, human vitronectin, fibronectin and chondroitin sulfate types A, B and C. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | COL-94 |
| Target | Collagen IV |
| Isotype | IgG1 |
| Immunogen | human collagen type IV |
| Antigen Species | Human |
| Species Reactivity | Human |
| Species Does Not React With | Cat, Chicken, Goat, Rabbit, Rat, Sheep |
| Conjugation | Unconjugated |