|Full Name||retinoblastoma binding protein 8|
|Product Description||Rabbit polyclonal antibody to CtIP (retinoblastoma binding protein 8)|
|Background||The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq]|
|Synonyms||CTIP antibody, RIM antibody, SAE2 antibody, RBBP8 antibody, sporulation in the absence of SPO11 protein 2 homolog antibody, DNA endonuclease RBBP8 antibody, CTBP-interacting protein antibody, RBBP-8 antibody, retinoblastoma binding protein 8 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CtIP. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (95%)|