|Full Name||cullin 5|
|Product Description||Rabbit Polyclonal antibody to Cullin 5 (cullin 5)|
|Background||Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. |
|Synonyms||VACM-1 antibody, VACM1 antibody, CUL5 antibody, vasopressin-activated calcium-mobilizing receptor 1 antibody, CUL-5 antibody, cullin-5 antibody, Vasopressin-activated calcium-mobilizing receptor-1 antibody, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody, cullin 5 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Cullin 5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Cat, Rabbit|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Xenopus laevis (99%), Cat (99%), Rabbit (100%)|