Cyclin A2 antibody
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||49 kDa (note)
|Positive Controls||293T , HeLa , A375 , Neuro2A , SK-N-SH , IMR32 , SK-N-AS , PC-12 , HeLa(100 µg/ml Bleomycin treatment for 24 hr) , *PC3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cyclin A2|
|Product Description||Rabbit Polyclonal antibody to Cyclin A2 (cyclin A2)|
|Background||The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq]|
|Synonyms||CCN1 antibody, CCNA antibody, CCNA2 antibody, cyclin-A antibody, cyclin-A2 antibody, cyclin A2 antibody|
|Cellular Localization||Nucleus , Cytoplasm|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cyclin A2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (89%), Rabbit (83%), Rhesus Monkey (98%), Bovine (84%)|