|Full Name||cyclin H|
|Product Description||Rabbit Polyclonal antibody to Cyclin H (cyclin H)|
|Background||The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. [provided by RefSeq]|
|Synonyms||CAK antibody, p34 antibody, p37 antibody, CCNH antibody, MO15-associated protein antibody, CAK complex subunit antibody, cyclin-H antibody, cyclin-dependent kinase-activating kinase complex subunit antibody, CDK-activating kinase complex subunit antibody, cyclin H antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cyclin H. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (94%), Pig (96%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (93%)|