Cyclophilin A antibody [N1C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||18 kDa (note)
|Positive Controls||Raji WCE , Raji C+M , Raji NE , Molt-4 , Raji , Mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||peptidylprolyl isomerase A (cyclophilin A)|
|Product Description||Rabbit Polyclonal antibody to Cyclophilin A (peptidylprolyl isomerase A (cyclophilin A))|
|Background||This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq]|
|Synonyms||CYPA antibody, CYPH antibody, MGC117158 antibody, MGC12404 antibody, MGC23397 antibody, PPIA antibody, cyclophilin antibody, PPIase A antibody, rotamase A antibody, peptidyl-prolyl cis-trans isomerase A antibody, cyclosporin A-binding protein antibody, T cell cyclophilin antibody, peptidylprolyl isomerase A (cyclophilin A) antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cyclophilin A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Cat, Pig, Rabbit, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (96%), Cat (97%), Pig (99%), Rabbit (96%), Chicken (92%), Sheep (99%), Rhesus Monkey (100%), Bovine (81%)|