|Full Name||cysteinyl leukotriene receptor 1|
|Product Description||Rabbit polyclonal antibody to CysLT 1 Receptor (cysteinyl leukotriene receptor 1)|
|Background||The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq]|
|Synonyms||CYSLT1 antibody, CYSLT1R antibody, CYSLTR antibody, HG55 antibody, HMTMF81 antibody, MGC46139 antibody, CYSLTR1 antibody, cysteinyl leukotriene receptor 1 antibody, cysteinyl leukotriene D4 receptor antibody, LTD4 receptor antibody, G-protein coupled receptor HG55 antibody|
|Cellular Localization||Cell membrane |
|Target||CysLT 1 Receptor |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CysLT 1 Receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (100%)|