|Full Name||keratin 8|
|Product Description||Rabbit Polyclonal antibody to Cytokeratin 8 (keratin 8)|
|Background||This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]|
|Synonyms||CARD2 antibody, CK8 antibody, CYK8 antibody, K2C8 antibody, K8 antibody, KO antibody, KRT8 antibody, cytokeratin-8 antibody, type-II keratin Kb8 antibody, cytokeratin 8 antibody, "keratin, type II cytoskeletal 8 antibody", keratin 8 antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (83%), Xenopus laevis (85%), Dog (91%), Pig (91%), Rhesus Monkey (99%), Bovine (90%)|