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Acidic Cytokeratin antibody [AE1]

Cat. No. GTX80320

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AE1

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Rabbit, Bovine, Chicken, Pig, Monkey
Package
100 μl ($399)
See all Acidic Cytokeratin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Product Note

Recognizes low molecular weight cytokeratins CK 10, CK14, CK15, CK16 and CK19 of the acidic family.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human epidermal keratins

Purification

Protein G

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

EPPK Antibody , keratin 1 Antibody , CK1 Antibody , EHK1 Antibody , KRT1A Antibody , K1 Antibody , KRT1 Antibody , EHK Antibody , NEPPK Antibody

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

Clone Reference

Chamcheu JC et al. J Dermatol Sci 2009; 53 (3):198-206 Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399