| Full Name | Rho GDP dissociation inhibitor (GDI) beta |
| Product Description | Mouse monoclonal [97A1015] to D4 GDI |
| Background | D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis. |
| Synonyms | Ly-GDI, D4 GDI, 602843, 397, P52566, RAP1GN1, GDIA2, D4, LyGDI, ARHGDIB, GDID4, Ly GDI |
| Cellular Localization | Cytoplasmic and Nuclear |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | 97A1015 |
| Target | D4 GDI |
| Isotype | IgG1 |
| Immunogen | Synthetic peptide corresponding to amino acid residue(s) in the Fas-induced cleavage site of human D4-GDI. |
| Antigen Species | Human |
| Species Reactivity | Human |