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D4 GDI antibody

Anti-D4 GDI antibody used in IHC (Paraffin sections) (IHC-P). GTX15198
Anti-D4 GDI antibody used in IHC (Paraffin sections) (IHC-P). GTX15198

Cat. No. GTX15198

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
500 μl ($399)

APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at a concentration of 1 μg/ml for 2hours. Predicted molecular weight: 23 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

23 kDa. ( Note )

Positive Control

Placenta and tonsil

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Rho GDP dissociation inhibitor beta , D4 , GDIA2 , GDID4 , LYGDI , Ly-GDI , RAP1GN1 , RhoGDI2

Cellular Localization

Cytoplasm, cytosol

Background

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]

Database

  • Gene ID: 397 ARHGDIB
  • UniProt: P52566 ARHGDIB

Research Area

DATA IMAGES

Anti-D4 GDI antibody used in IHC (Paraffin sections) (IHC-P). GTX15198

GTX15198 IHC-P Image

GTX15198 staining D4 GDI in human tonsil by Immunohistochemistry (FFPE-sections).

Anti-D4 GDI antibody used in IHC (Paraffin sections) (IHC-P). GTX15198

GTX15198 IHC-P Image

Human Placenta stained with anti-D4-GDI antibody (GTX15198)

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399