Dab1 antibody [N1N3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||64 kDa (note)
|Positive Controls||NT2D1 , IMR32 , U87-MG , MCF-7 , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||disabled homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Dab1 (disabled homolog 1 (Drosophila))|
|Background||The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]|
|Synonyms||DAB1 antibody, disabled homolog 1 antibody, disabled homolog 1 (Drosophila) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Dab1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken|
|Predict Reactivity Note||Rat (100%), Pig (100%), Chicken (91%)|